a case of hypogonadotropic hypogonadism caused by opioid treatment for nonmalignant chronic pain

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ID: 255997
2012
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Abstract
We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment.
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tabuchi2012casea Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Yukiko Tabuchi;Tetsuyuki Yasuda;Hideaki Kaneto;Tetsuhiro Kitamura;Junji Kozawa;Michio Otsuki;Akihisa Imagawa;Aya Nakae;Youichi Matsuda;Hironobu Uematsu;Takashi Mashimo;Masahiko Shibata;Iichiro Shimomura
Journal Frontiers in pharmacology
Year 2012
DOI
10.1155/2012/740603
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