review paper raynaud’s phenomenon: new aspects of pathogenesis and the role of nailfold videocapillaroscopy

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ID: 254328
2015
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Abstract
Raynaud’s phenomenon (RP) refers to paroxysmal pallor or cyanosis of the digits of the hands or feet and, infrequently, the tips of the nose or ears (acral parts) owing to cold-induced vasoconstriction of the digital arteries, precapillary arterioles, and cutaneous arteriovenous shunts. Raynaud’s phenomenon reflects an exaggeration of normal central and local vasomotor responses to cold or emotion. Raynaud’s phenomenon has been classified as primary or secondary, depending on whether it occurs as an isolated condition or is associated mainly with a connective tissue disease. Dysregulation of autonomic and sensitive nerve fibers, functional and structural vessel changes, and intravascular alterations can be observed in the pathogenesis of RP. Nailfold videocapillaroscopy (NVC) is the best non-invasive and repetitive diagnostic technique for detecting morpho-functional changes in the microcirculation. Nailfold videocapillaroscopy is accepted in early diagnosis and monitoring of primary and secondary RP.
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kuryliszyn-moskal2015rheumatologyreview Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Anna Kuryliszyn-Moskal;Jacek Kita;Anna Hryniewicz
Journal Ìnformacìjnì tehnologìï v osvìtì
Year 2015
DOI
10.5114/reum.2015.51508
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