Óxido nítrico inalatório para crianças com síndrome do desconforto respiratório agudo inhaled nitric oxide for children with acute respiratory distress syndrome
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Abstract
BACKGROUND AND OBJECTIVE: The objective of this study was to review the literature on inhaled nitric oxide to children with acute respiratory distress syndrome. CONTENTS: A review of literature and selection of the most important publications on inhaled nitric oxide, using the MedLine and Cochrane Systematic Review Databases. This review was organized as follows: introduction; metabolism and biological effects; clinical applications; dosage, gas administration and weaning process; warnings and side-effects. Inhaled nitric oxide use was described in acute respiratory distress syndrome. CONCLUSIONS: Inhaled nitric oxide as the first vasodilator to produce selective pulmonary vasodilation has beneficial effects on gas exchange and ventilation, improving outcome in children with severe hypoxia. It is safe when administered in intensive care units under strict surveillance and monitoring. Further studies should be concentrated on early treatment, when acute respiratory distress syndrome is potentially reversible.
| Reference Key |
fioretto2006revistaxido
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|---|---|
| Authors | ;José Roberto Fioretto;Mário Ferreira Carpi;Rossano César Bonatto;Sandra Mara Queiroz Ricchetti;Marcos Aurélio de Moraes |
| Journal | Database : the journal of biological databases and curation |
| Year | 2006 |
| DOI |
10.1590/S0103-507X2006000400015
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| URL | |
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