invasive medullary thymoma associated with myasthenia gravis: an unusual case miastenia gravis em um paciente com timoma medular invasivo: relato de caso

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2000
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Abstract
Thymomas are tumors characterized by a remarkable morphological heterogeneity and variable clinical behavior. This tumor has unique clinical associations, most notably with hematological abnormalities and myasthenia gravis. According with the Müller-Hermelink criteria, there are significant differences between the histological types of thymomas and the association with myasthenia gravis. Among the different histological types, medullary thymoma is the least frequent variant associated with this autoimmune disease. In this report we describe a case of medullary thymoma presenting in a 71-year- old woman with a myasthenic syndrome.
Os timomas são tumores caracterizados por grande heterogeneidade morfológica e comportamento clínico variável. Este tumor apresenta associações clínicas singulares, principalmente com doenças hematológicas e com a miastenia gravis. De acordo com a classificação de Müller-Hermelink, existem diferenças significativas entre as variedades histológicas dos timomas e sua associação com a miastenia gravis. Entre os diferentes tipos histológicos, o timoma medular é a variante menos frequentemente associada com esta doença autoimune. Neste relato, nós descrevemos caso de timoma medular em uma paciente de 71 anos de idade com síndrome miastênica.
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Authors ;JORGE S. REIS FILHO;MARIA FERNANDA MILANEZI;CHRISTIANO G. MOREIRA;LINEU C. WERNECK;PAULO BOSCARDIN;SERGIO OSSAMU IOSHII;FERNANDO C. SCHMITT
Journal communications in computer and information science
Year 2000
DOI
10.1590/S0004-282X2000000600020
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600020
Keywords
immunohistochemistry myasthenia gravis neuropsychiatry biological psychiatry müller-hermelink classificationneurosciences

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