development of a capillary electrophoresis method for the simultaneous determination of cephalosporins

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ID: 251580
2013
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Abstract
A rapid and simple capillary electrophoresis method has been developed for the simultaneous determination of six extensively used cephalosporin antibiotics (cefaclor, cefadroxil, cefalexin, cefuroxim, ceftazidim, ceftriaxon). The determination of cephalosporins was performed at a pH 6.8, using a 25 mM phospate - 25 mM borate mixed buffer, + 25 kV voltage at a temperature of 25 °C. We achieved a baseline separation in approximately 10 minutes. The separation resolution was increased by addition of an anionic surfactant, 50 mM sodium dodecyl sulfate, to the buffer solution. The proposed separation was evaluated on the basis of detection and quantification limits, effective electrophoretic mobility and relative standard deviation for migration times and peak areas.
Reference Key
gabriel2013journaldevelopment Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Hancu Gabriel;Kelemen Hajnal;Rusu Aura;Gyéresi Árpád
Journal meditsinskaia radiologiia
Year 2013
DOI
10.2298/JSC121117028H
URL
http://www.doiserbia.nb.rs/img/doi/0352-5139/2013/0352-51391300028H.pdf
Keywords
cephalosporins comparative and uniform law jurisprudencesocial sciencesfinance emerging marketslawlaw in general

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