current immunotherapies for sarcoma: clinical trials and rationale

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ID: 251566
2016
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Abstract
Sarcoma tumors are rare and heterogeneous, yet they possess many characteristics that may facilitate immunotherapeutic responses. Both active strategies including vaccines and passive strategies involving cellular adoptive immunotherapy have been applied clinically. Results of these clinical trials indicate a distinct benefit for select patients. The recent breakthrough of immunologic checkpoint inhibition is being rapidly introduced to a variety of tumor types including sarcoma. It is anticipated that these emerging immunotherapies will exhibit clinical efficacy for a variety of sarcomas. The increasing ability to tailor immunologic therapies to sarcoma patients will undoubtedly generate further enthusiasm and clinical research for this treatment modality.
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mitsis2016sarcomacurrent Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Demytra Mitsis;Valerie Francescutti;Joseph Skitzki
Journal the journal of physiology
Year 2016
DOI
10.1155/2016/9757219
URL
http://dx.doi.org/10.1155/2016/9757219
Keywords
neoplasms Oncology including cancer and carcinogens tumors

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