roles of nf-κb in cancer and inflammatory diseases and their therapeutic approaches
Clicks: 258
ID: 251385
2016
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Abstract
Nuclear factor-κB (NF-κB) is a transcription factor that plays a crucial role in various biological processes, including immune response, inflammation, cell growth and survival, and development. NF-κB is critical for human health, and aberrant NF-κB activation contributes to development of various autoimmune, inflammatory and malignant disorders including rheumatoid arthritis, atherosclerosis, inflammatory bowel diseases, multiple sclerosis and malignant tumors. Thus, inhibiting NF-κB signaling has potential therapeutic applications in cancer and inflammatory diseases.
| Reference Key |
park2016cellsroles
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|---|---|
| Authors | ;Mi Hee Park;Jin Tae Hong |
| Journal | Frontiers in psychology |
| Year | 2016 |
| DOI |
10.3390/cells5020015
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