pediatric papillary renal cell carcinoma in a horseshoe kidney: a case report with review of the literature
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ID: 251374
2015
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Abstract
Renal cell carcinoma is the most common malignancy of the kidney in adults. In children, however, it only accounts for an estimated 1.8 to 6.3% of all pediatric malignant renal tumors. Papillary renal cell carcinoma is the second most common type of renal cell carcinoma in children. We present the case of a 12-year-old boy with a 2-month history of abdominal pain, unexplained weight loss, and gross hematuria. Computed tomography revealed a horseshoe kidney and a well-defined mass of 4 cm arising from the lower pole of the right kidney. Microscopically the tumor was composed of papillae covered with cells with abundant eosinophilic cytoplasm and high-grade nuclei with prominent nucleoli. Immunohistochemistry was performed; EMA, Vimentin, and AMACR were strongly positive while CK7, CD10, RCC antigen, TFE3, HMB-45, and WT-1 were negative. Currently, 10 months after the surgical procedure, the patient remains clinically and radiologically disease-free.
| Reference Key |
loya-solis2015casepediatric
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|---|---|
| Authors | ;Abelardo Loya-Solis;Lucía Alemán-Meza;Luis Carlos Canales-Martínez;Rodolfo Franco-Márquez;Alim Adriana Rincón-Bahena;Karla María Nuñez-Barragán;Raquel Garza-Guajardo;Marco Antonio Ponce-Camacho |
| Journal | nuclear medicine and biology |
| Year | 2015 |
| DOI |
10.1155/2015/841237
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| URL | |
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