spontaneous t cell proliferation: a physiologic process to create and maintain homeostatic balance and diversity of the immune system

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2018
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Abstract
Naive T lymphocytes undergo heterogeneous proliferative responses when introduced into lymphopenic hosts, referred to as “homeostatic proliferation” and “spontaneous proliferation.” Spontaneous proliferation is a unique process through which the immune system generates memory phenotype cells with increasing T cell receptors repertoire complexity. Here, the mechanisms that initiate and control spontaneous proliferation are discussed.
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Authors ;Booki Min
Journal sudebno-meditsinskaia ekspertiza
Year 2018
DOI
10.3389/fimmu.2018.00547
URL
http://journal.frontiersin.org/article/10.3389/fimmu.2018.00547/full
Keywords
t cells homeostasis proliferation lymphocytes allergy

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