para que existem as regras de nomenclatura genética? why are there rules for genetic nomenclature?

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ID: 251078
2005
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Ranked #75 of 100 articles by views in journal of computational and graphical statistics : a joint publication of american statistical association, institute of mathematical statistics, interface foundation of north america

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Abstract
Na comunicação científica, precisamos respeitar os princípios de clareza, precisão, comunicabilidade e consistência. Para isso, existe um comitê de nomenclatura genética, cuja função é assegurar que cada gene humano tenha um nome e símbolo únicos que sejam usados consistentemente na literatura científica. Apesar dos esforços, ainda encontramos textos onde o autor se refere a um gene usando um símbolo obsoleto, ou não faz a distinção adequada entre o gene e a proteína, prejudicando a compreensão por parte do leitor. Com isso em mente, apresento uma revisão das regras de nomenclatura de genes e diversos recursos disponíveis através da Internet para encontrar os nomes adequados dos genes, enfatizando aqueles envolvidos em câncer.
In scientific writings, we must strive for clarity, accuracy, objectivity, and consistency. Hence the purpose of a genetic nomenclature committee that assigns a unique name and symbol for each human gene, ensuring their unequivocal identification in the scientific literature. Despite these efforts, we still see publications using outdated symbols for genes, and authors that fail to distinguish between gene and protein in their writings. Since such mistakes can severely hinder the readers' comprehension, I present a review of gene nomenclature guidelines, and of the various Internet tools for retrieving approved gene names and symbols, highlighting those that are important in the study of cancer.
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Authors ;Alessandra Splendore
Journal journal of computational and graphical statistics : a joint publication of american statistical association, institute of mathematical statistics, interface foundation of north america
Year 2005
DOI
10.1590/S1516-84842005000200020
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842005000200020
Keywords
nomenclature

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