extradigestive manifestation of helicobacter pylori infection in children and adolescents

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ID: 248254
2005
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Abstract
Helicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. More recently, multiple publications have advocated a role for H pylori infection in causing a variety of extraintestinal manifestations. Many of these reports suffer from being case reports or case series without adequate controls. As a result, purported manifestations may simply be coincidental in nature. On the other hand, increasing evidence supports H pylori infection as a cause of sideropenic (refractory iron deficiency) anemia. Moderate evidence supports H pylori gastric infection as a cause of some cases of immune thrombocytopenic purpura due to molecular mimicry. Guidelines should be adjusted in accordance with advancing knowledge in the field.
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sherman2005canadianextradigestive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Philip M Sherman;Frank YH Lin
Journal indian journal of pharmacology
Year 2005
DOI
10.1155/2005/971974
URL
http://dx.doi.org/10.1155/2005/971974
Keywords
Gastroenterology diseases of the digestive system

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