the synthesis of a novel bibenzopyran relied on electrooxydation of malloapelta b by cyclic voltammetry

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ID: 245816
2017
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Abstract
A novel bibenzopyran named bimalloapelta (1) was synthesized relying on electrooxydation of malloapelta B by cyclic voltammetry in acetonitril adding LiClO4 0.1 M as supporting electrolyte. Its structure determination based on extensive NMR studies and ESI mass spectral measurements. The new compound showed significant cytotoxicity againsts two cancer cell lines as human hepatocellular carcinoma (Hep-2; IC50: 0.46 µg/m) and rhabdosarcoma (RD; IC50: 0.33 µg/m). These results were the same that of  malloapelta B  (Hep-2, IC50: 0.49 µg/ml and  KB, IC50: 0.54 µg/ml).
Reference Key
binh2017aseanthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Phan Thi Binh;Bui Hai Ninh;Chau Van Minh;Nguyen Hoai Nam;Le Mai Huong;Phan Van Kiem
Journal atmospheric environment
Year 2017
DOI
10.29037/ajstd.210
URL
http://www.ajstd.org/index.php/ajstd/article/view/210
Keywords
Cytotoxicity

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