synthesis, structure, physicochemical properties and catecholase-like activity of a new dicopper(ii) complex

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ID: 245551
2001
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Abstract
The synthesis, characterization and catecholase activity studies of the complex [Cu2(H2bbppnol)(mu-OAc)(mu-ClO 4)]ClO4·H2O·EtOAc containing the dinucleating ligand N,N'-2-hydroxybenzyl-N,N' -2-pyridylmethyl-2-hydroxypropane-1,3-diamine (H3bbppnol) are presented here. The complex was characterized by IR, electronic and EPR spectroscopies, cyclic voltammetry, magnetic susceptibility measurements and X-ray crystallography. The catecholase-like activity of the complex was determined spectrophotometrically by monitoring the oxidation of 3,5-di-tert-butylcatechol to the corresponding o-benzoquinone in O2-saturated methanol/aqueous buffer (pH 8) mixtures at 25ºC. The complex was able to oxidize the model substrate with a turnover number of 0.0057 s-1.
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Authors ;Neves Ademir;Rossi Liane M.;Bortoluzzi Adailton J.;Mangrich Antônio S.;Haase Wolfgang;Werner Rüdiger
Journal british journal of dermatology
Year 2001
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