synthesis and analgesic activity of novel derivatives of 1,2-substituted benzimidazoles
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ID: 245112
2013
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Abstract
A series of novel 2-phenylhydrazinomethyl and 2-(2-hydroxyphenyl)-benzimidazole derivatives substituted at the N1-position of benzimidazole nucleus were synthesized as well as screened for analgesic activity. Some of these compounds showed promising analgesic activity when compared with the standard drug diclofenac sodium. The incorporation of a phenylhydrazinomethyl nucleus at 2-position of benzimidazole compound gave a biologically active pharmacophore.
| Reference Key |
srivastava2013journalsynthesis
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|---|---|
| Authors | ;Shobhit Srivastava;S. N. Pandeya;Meena K. Yadav;B. K. Singh |
| Journal | british journal of psychology (london, england : 1953) |
| Year | 2013 |
| DOI |
10.1155/2013/694295
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| URL | |
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