in vitro comparison of the effect of iranian nystatin and chlorhexidine mouthwashes with foreign samples on standard and local isolated strains of candida albicans
Clicks: 317
ID: 241064
2006
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
76.1
/100
317 views
211 readers
Trending
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #9 of 54 articles by views in american journal of alzheimer's disease and other dementias
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background and Aim: Chlorhexidine is a mouthwash with known antibacterial effect but its antifungal effect is not clear. The aim of this study was to compare the antimicrobial effects of nystatin and chlorhexidine mouthwashes (one Iranian product and the other, commercial) on Candida albicans under in vitro condition. Materials and Methods: In this experimental study, the strains of Candida albicans used consisted of one standard strain (PTCC 5027) and ten local isolates. The latter were obtained from patients referred to different dental clinics in Kerman city. The specimens were taken from the gum and palate area by sterile swabs and dipped into Stewards transport medium, transferred to the laboratory within one hour, and cultured on Sabauraud dextrose Agar. Colonies showing the characteristic appearance of Candida were further cultured and routine differential tests including germ tube formation were performed to confirm the diagnosis of C.albicans. These were used to prepare a microbial cell suspension of 0.5 Mc Farland concentration. Each cell suspension was inoculated over duplicate plates of SDA and 4 wells of 5 mm diameter were made using sterile cork borers. Each previously coded mouthwash was placed in corresponding well and incubated for 24-48 hours and the diameter of inhibition zone was measured with ruler. The minimum inhibitory concentration (MIC) of each mouthwash for each isolate of Candida albicans was determined using dilution tube technique. Data were analyzed by SPSS package using proper statistical tests with P<0.05 as the limit of significance. Results: There was a significant difference between the antimicrobial effects of the four tested mouthwashes. The results indicated that Iranian nystatin mouthwash had the greatest effect and the average inhibition zone from the highest to the lowest was associated with Iranian nystatin, foreign nystatin, Iranian chlorhexidine and foreign chlorhexidine respectively. The MIC determination revealed that generally nystatin was more effective than chlorhexidine. No statistical difference was seen between the Iranian and foreign samples. Conclusions: Despite the antifungal effects of chlorhexidine, more investigations on different strains of C.albicans is required before recommending its cilinical application.
| Reference Key |
z2006journalin
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Ataei Z;Abdollahi H;Salarzadeh M |
| Journal | american journal of alzheimer's disease and other dementias |
| Year | 2006 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.