microrna in human glioma

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ID: 240322
2013
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Abstract
Glioma represents a serious health problem worldwide. Despite advances in surgery, radiotherapy, chemotherapy, and targeting therapy, the disease remains one of the most lethal malignancies in humans, and new approaches to improvement of the efficacy of anti-glioma treatments are urgently needed. Thus, new therapeutic targets and tools should be developed based on a better understanding of the molecular pathogenesis of glioma. In this context, microRNAs (miRNAs), a class of small, non-coding RNAs, play a pivotal role in the development of the malignant phenotype of glioma cells, including cell survival, proliferation, differentiation, tumor angiogenesis, and stem cell generation. This review will discuss the biological functions of miRNAs in human glioma and their implications in improving clinical diagnosis, prediction of prognosis, and anti-glioma therapy.
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yang2013cancersmicrorna Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Yi Yang;Mengfeng Li;Jun Li;Lei Liu;Wei Li;Jie Yuan
Journal The Journal of investigative dermatology
Year 2013
DOI
10.3390/cancers5041306
URL
http://www.mdpi.com/2072-6694/5/4/1306
Keywords
glioma microrna crosstalk Oncology including cancer and carcinogens tumors

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