prevalência da doença renal crônica nos estágios 3, 4 e 5 em adultos prevalence of chronic kidney disease, stages 3, 4 and 5 in adults
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2009
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Abstract
INTRODUÇÃO: Medidas que otimizem a detecção precoce da doença renal crônica (DRC) são fundamentais para o retardo na evolução da doença e diminuição do aporte de indivíduos às terapias renais de substituição. OBJETIVOS: Estimar a prevalência da DRC em seus estágios 3, 4 e 5, utilizando registros laboratoriais de indivíduos submetidos a dosagem de creatinina sérica por causas diversas em laboratório da rede particular do município de Juiz de Fora, no período de 2004 e 2005. MÉTODOS: O estudo foi consubstanciado pelo cálculo estimado da filtração glomerular, utilizando a equação do estudo MDRD (Modification of diet in renal disease), e seguiu os critérios propostos pelo K/DOQI (Kidney Disease Outcomes Quality Initiative) para o diagnóstico e classificação da DRC. RESULTADOS: A prevalência encontrada foi de 9,6%, sendo 12,2% no sexo feminino, 5,8% no sexo masculino, 3,7% em indivíduos abaixo de 60 anos e 25,2% acima de 60 anos. CONCLUSÃO: Os resultados evidenciam a prevalência da DRC não apenas como um indicador epidemiológico, mas demonstram um aspecto operacional alternativo para otimizar a capacidade de detecção dos casos e permitem sugerir a inclusão do cálculo da filtração glomerular como um dado complementar aos resultados das dosagens de creatinina sérica fornecidos pelos laboratórios.
INTRODUCTION: Strategies that optimize early diagnosis of chronic kidney disease (CKD) are paramount to decrease progression of the disease and the burden of patients needing renal replacement therapy. OBJECTIVE: The aim of this study was to determine the prevalence of CKD stage 3, 4 and 5 in people submitted to dosage of serum creatinine due to different causes, employing a dataset from a private laboratory of the city of Juiz de Fora comprising the years 2004 and 2005. METHODS: Diagnosis and staging of CKD were based upon glomerular filtration rate (GFR) estimated from serum creatinine as recommended by the KDOQI of the National Kidney Foundation and the Brazilian Society of Nephrology. RESULTS: Prevalence of CKD stage 3, 4 and 5 was of 9.6%, with 12.2%, 5.8%, 25.2% and 3.7% among women, men, people >60 and < 60 years of age, respectively. CONCLUSION: Prevalence of CKD found in our study may not only be interpreted as an epidemiologic indicator, but also discloses an alternative operational strategy to identify the disease. Furthermore it supports a proposal to include the estimation of GFR from serum creatinine in the laboratory report as an important and simple tool for early diagnosis of CKD.
INTRODUCTION: Strategies that optimize early diagnosis of chronic kidney disease (CKD) are paramount to decrease progression of the disease and the burden of patients needing renal replacement therapy. OBJECTIVE: The aim of this study was to determine the prevalence of CKD stage 3, 4 and 5 in people submitted to dosage of serum creatinine due to different causes, employing a dataset from a private laboratory of the city of Juiz de Fora comprising the years 2004 and 2005. METHODS: Diagnosis and staging of CKD were based upon glomerular filtration rate (GFR) estimated from serum creatinine as recommended by the KDOQI of the National Kidney Foundation and the Brazilian Society of Nephrology. RESULTS: Prevalence of CKD stage 3, 4 and 5 was of 9.6%, with 12.2%, 5.8%, 25.2% and 3.7% among women, men, people >60 and < 60 years of age, respectively. CONCLUSION: Prevalence of CKD found in our study may not only be interpreted as an epidemiologic indicator, but also discloses an alternative operational strategy to identify the disease. Furthermore it supports a proposal to include the estimation of GFR from serum creatinine in the laboratory report as an important and simple tool for early diagnosis of CKD.
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bastos2009revistaprevalncia
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| Authors | ;Rita Maria Rodrigues Bastos;Marcus Gomes Bastos;Luís Cláudio Ribeiro;Ricardo Villela Bastos;Maria Teresa Bustamante Teixeira |
| Journal | acta crystallographica section e |
| Year | 2009 |
| DOI |
10.1590/S0104-42302009000100013
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