cognitive decline tracks motor progression and not disease duration in parkinson patients

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ID: 239006
2007
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Abstract
BD Riggeal1, GP Crucian1, P Seignourel2, CE Jacobson IV1, MS Okun1, RL Rodriguez1, Hubert H Fernandez11Department of Neurology; 2Department of Community Health and Psychology, University of Florida, Gainesville, FL, USAAbstract: We performed an analysis of prospectively-acquired cross sectional data on 106 Parkinson disease (PD) patients who underwent comprehensive neuropsychological testing and the Unified Parkinson Disease Rating Scale (UPDRS) motor scale. A significant correlation between the UPDRS motor and neuropsychological tests in all cognitive domains except for general intelligence and visuo-spatial function was seen. In this study, cognitive decline within this PD cohort correlated with motor impairment but not disease duration. Our findings suggest that overall cognitive impairment (except visuospatial dysfunction) may track motor progression in PD more than duration of disease. Longitudinal studies are needed to confirm our results.Keywords: Parkinson, dementia, cognition, visual-spatial dysfunction
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riggeal2007neuropsychiatriccognitive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;BD Riggeal;GP Crucian;P Seignourel;CE Jacobson IV;MS Okun;et al
Journal journal of crystal growth
Year 2007
DOI
DOI not found
URL
http://www.dovepress.com/cognitive-decline-tracks-motor-progression-and-not-disease-duration-in-a976
Keywords
neurosciences diseases of the nervous system neuropsychiatryneurology biological psychiatry

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