effect of 6 weeks of swimming training and aloe vera extract supplementation on the serum levels of cyclooxygenase-2 and vascular endothelial growth factor in mice with breast cancer
Clicks: 298
ID: 238271
2017
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Emerging Content
66.1
/100
298 views
226 readers
Trending
AI Quality Assessment
Not analyzed
Readership in this journal
EmergingRanked #26 of 69 articles by views in journal of consulting and clinical psychology
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background and Objectives: Regular physical activity is associated with improved quality of life and reductions of cancer-related mortality, but the underlying mechanisms are unclear. Moreover, Aloe vera may have anti-tumor and anti-inflammatory effects. In the current study, the effect of 6 weeks of swimming trainings along with Aloe vera supplementation, was investigated on serum levels of cyclooxygenase-2 and vascular endothelial growth factor in mice with breast cancer.
Methods: In this quasi-experimental study, 35Balb/c mice were acclimatized with laboratory conditions and swimming trainings, then mouse adenocarcinoma tumor balk was transplanted subcutaneously and after a week, they were divided into 7-animal groups, including exercise, exercise + extract, extract, and control (cancer). The fifth group )as the healthy control( included 7 mice. The exercise groups underwent swimming training for 6 weeks, and the extract groups also received 300mg/kg/day of aloe vera extract for 6 weeks. Blood samples were taken from the right ventricle 48 hours after the last session. The data were analyzed using one-way ANOVA at the significance level of p<0.05.
Results: The serum levels of COX-2 and VEGF significantly increased with tumor induction (p<0.05). After 6 weeks, VEGF levels in both exercise groups and COX-2 levels in the extract group, were lower compared to the cancer control group (p<0.05); However, these levels were higher than the healthy control group.
Conclusion: Based on the results, swimming and aloe vera supplementation may attenuate the increase of circulatory levels of COX-2 and VEGF caused by tumor induction but cannot normalize the elevated levels.
| Reference Key |
barari2017majallah-ieffect
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;ALireza barari;parvin farzanegi;jabbar bashiri;fatemeh kochpideh;farhad gholami |
| Journal | journal of consulting and clinical psychology |
| Year | 2017 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.