fecal microbiota transplantation: current applications, effectiveness, and future perspectives

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ID: 236400
2016
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Abstract
Fecal microbiota transplantation (FMT) is the infusion of liquid filtrate feces from a healthy donor into the gut of a recipient to cure a specific disease. A fecal suspension can be administered by nasogastric or nasoduodenal tube, colonoscope, enema, or capsule. The high success rate and safety in the short term reported for recurrent Clostridium difficile infection has elevated FMT as an emerging treatment for a wide range of disorders, including Parkinson’s disease, fibromyalgia, chronic fatigue syndrome, myoclonus dystopia, multiple sclerosis, obesity, insulin resistance, metabolic syndrome, and autism. There are many unanswered questions regarding FMT, including donor selection and screening, standardized protocols, long-term safety, and regulatory issues. This article reviews the efficacy and safety of FMT used in treating a variety of diseases, methodology, criteria for donor selection and screening, and various concerns regarding FMT.
Reference Key
choi2016clinicalfecal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Hyun Ho Choi;Young-Seok Cho
Journal annals of intensive care
Year 2016
DOI
10.5946/ce.2015.117
URL
http://www.e-ce.org/upload/pdf/ce-2015-117.pdf
Keywords
colitis fecal microbiota transplantation infection Gastroenterology

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