the relation between enos −786 c/t, 4 a/b, mmp-13 rs640198 g/t, eotaxin 426 c/t, −384 a/g, and 67 g/a polymorphisms and long-term outcome in patients with coronary artery disease

Clicks: 158
ID: 236274
2015
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #132 of 193 articles by views in international journal of psychology : journal international de psychologie

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 193 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Aim. The purpose of this study is to determine the association between eotaxin 426 C/T, −384 A/G, 67 G/A, eNOS −786 T/C, 4 a/b, and MMP-13 rs640198 G/T and prognosis of patients with known CAD. Methods. From total of 1161 patients referred to coronary angiography, 532 patients with angiographically confirmed CAD were selected. Their long-term outcome was followed up using hospital database. Subsequent events were assessed in this study: death or combined endpoint-myocardial infarction, unstable angina pectoris, revascularization, heart failure hospitalization, and cardioverter-defibrillator implantation. Results. The multivariate Cox regression model identified age, smoking, and 3-vessel disease as significant predictors of all-cause death. Further analysis showed that eotaxin 67 G/A (GA + AA versus GG) and eotaxin −384 A/G (GG versus GA + AA) were significant independent prognostic factors when added into the model: HR (95% CI) 2.81 (1.35–5.85), p=0.006; HR (95% CI) 2.63 (1.19–5.83), p=0.017; eotaxin −384 A/G was significantly associated with the event-free survival, but it did not provide the prognostic information above the effect of two- or three-vessel disease. Conclusion. The A allele in eotaxin 67 G/A polymorphism is associated with worse survival in CAD patients.
Reference Key
kincl2015diseasethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Vladimír Kincl, Jan Máchal, Adéla Drozdová, Roman Panovský, Anna Vašků
Are you one of these authors? Claim your profile
Journal international journal of psychology : journal international de psychologie
Year 2015
DOI
10.1155/2015/232048
URL
http://dx.doi.org/10.1155/2015/232048
Keywords
Medicine (General)

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.