the effects of bifidobacterium bifidum (bbcwf) on proliferation of k562 cell line
Clicks: 259
ID: 235604
2017
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Steady Performance
30.0
/100
259 views
39 readers
AI Quality Assessment
Not analyzed
Readership in this journal
SteadyRanked #31 of 50 articles by views in artificial cells, nanomedicine, and biotechnology
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background & Objective: In the previous studies, the beneficial effects of oral administration of probiotic bacteria in treatment of some gastrointestinal cancer have been documented. The main aim of this study was to evaluate the direct effects of the bacterial cell wall extract Bifidobacterium bifidum on proliferation of human erythromyeloid cancer cell line K562.
Material & methods: After culturing the bacteria, and preparing cell wall fractions, dilutions of 1000, 2000, 4000 and 8000 µg/ml bacteria cell walls were prepared in sterile conditions. K562 cells and peripheral blood mononuclear cells (PBMC) were cultured in a conventional manner in the presence of different concentrations of bacteria from cell wall extract with the doxorubicin concentration of 0.1 mM. In order to assess the anticancer property of the abovementioned extract the MTT test was utilized. The T-Student test was used in order to analyze the data using SPSS 21.
Results: The minimum effective concentration of bacteria extract on the viability of K562 cells and PBMC was 2000 and 4000 µg/ml, respectively.
Conclusion: The selected bacterial extract killed more cancer cells than PBMC cells.
| Reference Key |
zarei2017journalthe
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Leila zarei;mysam abtahi foroshani;Atefeh Garajedagi;Hadi Esmaeili govarchin galeh |
| Journal | artificial cells, nanomedicine, and biotechnology |
| Year | 2017 |
| DOI |
DOI not found
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.