cd161 expressing human t cells
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ID: 235563
2011
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Abstract
Expression of the Natural Killer cell receptor CD161 has recently been identified on a subset of T cells, including both CD4+ T helper and CD8+ cytotoxic T cells. Expression of this molecule within the adult circulation is restricted to those T cells with a memory phenotype. However, the distinct properties of these T cell populations is yet to be fully determined, although expression of CD161 has been related to the secretion of interleukin 17, and therefore to a type 17 phenotype. Recent studies have aimed to determine both the origin of these cells and the significance of CD161 expression as either a marker of specific cell types or as an effector and regulator of lymphocyte function, and hence to characterise the role of these CD161+ cells within a variety of human diseases in which they have been implicated.
| Reference Key |
fergusson2011frontierscd161
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|---|---|
| Authors | ;Joannah R Fergusson;Vicki M Fleming;Paul eKlenerman;Paul eKlenerman |
| Journal | sudebno-meditsinskaia ekspertiza |
| Year | 2011 |
| DOI |
10.3389/fimmu.2011.00036
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| URL | |
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