toll-like receptor sensing of human herpesvirus infection

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ID: 235379
2012
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Abstract
Toll-like receptors (TLRs) are evolutionarily conserved pathogen sensors that constitute the first line of defense in the human immune system. Herpesviruses are prevalent throughout the world and cause significant disease in the human population. Sensing of herpesviruses via TLRs has only been documented in the last ten years and our understanding of the relationship between these sentinels of the immune system and herpesvirus infection has already provided great insight into how the host cell responds to viral infection. This report will summarize the activation and modulation of TLR signaling in the context of human herpesvirus infections.
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west2012frontierstoll-like Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;John A West;Sean M Gregory;Blossom eDamania
Journal electronic physician
Year 2012
DOI
10.3389/fcimb.2012.00122
URL
http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00122/full
Keywords
cytokines interferons innate immunity herpesvirus

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