influence of lifetime exposure of sublethal doses of cadmium to selected parameters of carbohydrate metabolism

Clicks: 207
ID: 234528
2012
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Abstract
The aim of the study was to assess the effects of exposure to low doses of cadmium dissolved in drinking water (at a concentration 200 times higher than the maximum permissible dose) on selected parameters of carbohydrate metabolism in 20 Wistar rats. Animals were divided into two groups – control and experimental groups exposed to low doses of cadmium chloride in concentration 20 μM of drinking water. We studied the biochemical parameters, as glucose, hemoglobin, glycated hemoglobin, lactate dehydrogenase and amylase in blood of rats. Glucose, hemoglobin, glycated hemoglobin and amylase levels increased, lactate dehydrogenase was no changed of rats exposed to cadmium. Good indicators of chronic intoxication by cadmium are elevated levels of glucose, hemoglobin and mainly glycated hemoglobin in blood. The evaluation results should be taken into account not only the data at the end of the experiment but for the entire duration of trials (i.e., more time steps), which results largely make objective.

doi:10.5219/231
Reference Key
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Authors ;František Ništiar;Iveta Cimboláková;Eva Lovásová;Jaroslava Nováková;Agnesa Lukačínová
Journal sensors
Year 2012
DOI
10.5219/231
URL
http://www.potravinarstvo.com/journal1/index.php/potravinarstvo/article/view/231
Keywords
cadmium glucose amylase haemoglobin foods and food supply lactate dehydrogenasenutrition

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