comparative study between endoscopic ultrasongraphy-assisted endoscopic mucosal resection and routine endoscopic mucosal resection treatment of esophageal precancerous lesions
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ID: 233973
2016
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Abstract
Objective: To compare the trauma between endoscopic ultrasongraphy-assisted endoscopic
mucosal resection and routine endoscopic mucosal resection treatment of esophageal
precancerous lesions. Methods: A total of 59 patients with esophageal precancerous lesions
who received endoscopic mucosal resection in our hospital between May 2013 and October
2016 were selected and divided into endoscope group and routine group who received
endoscopic ultrasongraphy-assisted endoscopic mucosal resection and routine endoscopic
mucosal resection respectively. Serum was collected immediately after operation to determine
the content of stress-related molecules, tumor markers and proliferation-related molecules,
and tumor tissue was collected to determine the expression of proliferation-related molecules.
Results: Immediately after operation, renin, angiotensin II, aldosterone, epinephrine,
norepinephrine, Cyfra21-1, SCC-Ag, TSGF, DDK-1, MACC1, c-met, CyclinB1, CDK1,
Survivin and Bcl-2 content in serum of ultrasound group were significantly lower than those
of normal group while MACC1, c-met, CyclinB1, CDK1, Survivin and Bcl-2 content in
tumor tissue were not significantly different from those of normal group. Conclusions: The
trauma of endoscopic ultrasongraphy-assisted endoscopic mucosal resection treatment of
esophageal precancerous lesions is lower than that of routine endoscopic mucosal resection,
the postoperative stress response is weaker and the leakage of tumor markers and proliferationrelated
molecules in the tissue is fewer.
| Reference Key |
gao2016journalcomparative
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|---|---|
| Authors | ;Jie Gao;Feng-Ting Wu;Ai-Lan Xian |
| Journal | journal of communications |
| Year | 2016 |
| DOI |
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