four narcolepsy cases after h1n1 infection or vaccination

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ID: 232909
2015
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Abstract
This report describes 4 narcolepsy cases that were developed after Influenza A/H1N1 infection or vaccination. The durations from Influenza A/H1N1 infection or vaccination to the symptom onset were 10 days, 2 weeks, 3 months, 6 months respectively. Among the four, two were teenagers or younger. One of them developed symptoms after Influenza A/H1N1 infection while three of them developed after vaccination. All went through polysomnography followed by multiple sleep latency tests for accurate diagnosis. All suffered from cataplexy. However, one of them presented with negative results in the human leukocyte antigen DQB1*0602 study. These cases suggest a possibility an association between H1N1/Influenza A virus and narcolepsy development via immune mechanism.
Reference Key
kim2015sleepfour Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Tae Won Kim;Hye Jin Kim;Dong Woo Kang;Hyun Jung Kwak;Seung Chul Hong
Journal Journal of experimental botany
Year 2015
DOI
10.17241/smr.2015.6.1.38
URL
http://www.sleepmedres.org/upload/pdf/smr-6-1-38.pdf
Keywords
narcolepsy vaccination neuropsychiatry biological psychiatry

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