crystal structure and hirshfeld surface analysis of 1-(2,4-dichlorobenzyl)-5-methyl-n-(thiophene-2-sulfonyl)-1h-pyrazole-3-carboxamide

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ID: 232043
2018
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Abstract
In the title compound, C16H13Cl2N3O3S2, the thiophene ring is disordered in a 0.762 (3):0.238 (3) ratio by an approximate 180° rotation of the ring around the S—C bond linking the ring to the sulfonyl unit. The dichlorobenzene group is also disordered over two sets of sites with the same occupancy ratio. The molecular conformation is stabilized by intramolecular C—H...Cl and C—H...N hydrogen bonds, forming rings with graph-set notation S(5). In the crystal, pairs of molecules are linked by N—H...O and C—H...O hydrogen bonds, forming inversion dimers with graph-set notation R22(8) and R12(11), which are connected by C—H...O hydrogen-bonding interactions into ribbons parallel to (100). The ribbons are further connected into a three-dimensional network by C—H...π interactions and π–π stacking interactions between benzene and thiophene rings, with centroid-to-centroid distances of 3.865 (2), 3.867 (7) and 3.853 (2) Å. Hirshfeld surface analysis has been used to confirm and quantify the supramolecular interactions.
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aydin2018actacrystal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Abdullah Aydin;Mehmet Akkurt;Zehra Tugce Gur;Erden Banoğlu
Journal Disability and rehabilitation
Year 2018
DOI
10.1107/S2056989018006242
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