new insights into regulatory t cells:exosome and non-coding rna mediated regulation of homeostasis, and resident regulatory t cells

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2016
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Abstract
Regulatory T (Treg) cells are a population of cells that are heterogeneous in origin and in functional activity. Treg cells constitute an essential counterbalance to adaptive immune responses. As key regulators of self-tolerance, Treg cells have been implicated in a number of pathologic processes and considered as therapeutic targets. Here, we summarize recent research regarding Treg cell origins and their functional classification, highlight the role of exosomes and non-coding RNA in modulating Treg cell homeostasis, and discuss the current understanding of resident Treg cells.
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Authors ;Peiyao Li;Peiyao Li;Peiyao Li;Changhong Liu;Changhong Liu;Changhong Liu;Zhibin Yu;Zhibin Yu;Zhibin Yu;Minghua Wu;Minghua Wu;Minghua Wu
Journal sudebno-meditsinskaia ekspertiza
Year 2016
DOI
10.3389/fimmu.2016.00574
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