impact upon clinical outcomes of translation of pna fish-generated laboratory data from the clinical microbiology bench to bedside in real time
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ID: 229258
2008
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Abstract
Tam Ly, Jyoti Gulia, Vasilios Pyrgos, Masashi Waga, Shmuel ShohamSection of Infectious Diseases, Washington Hospital Center, Washington DC, USAAbstract: Fluorescence in situ hybridization using peptide nucleic acid probes (PNA-FISH) differentiates Staphylococcus aureus from other Gram-positive-cocci in clusters (GPCC). 101/202 patients with GPCC+ blood cultures were randomly assigned to clinician-notification of PNA FISH results. Notifi cation was associated with reduced mortality (8% vs.17%, p = 0.05), further antibiotic use (median −2.5 days, p = 0.01), and trended toward reduced hospital stay and charges.
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| Authors | ;Tam Ly;Jyoti Gulia;Vasilios Pyrgos;Masashi Waga;Shmuel Shoham |
| Journal | liver transplantation : official publication of the american association for the study of liver diseases and the international liver transplantation society |
| Year | 2008 |
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