effects of creatine supplementation on high-intensity intermittent exercise: discrepancies and methodological appraisals

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ID: 228078
2008
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Abstract
After a brief review of the literature on the effects of creatine supplementation on high-intensity intermittent exercise performance, the main aim of this study was to discuss methodological differences between studies which could explain the discrepancies observed in the literature. The effects of creatine supplementation on high-intensity intermittent exercise performance have been investigated in depth. Although the results of much research demonstrates the effi cacy of this supplement, there is just as much evidence that does not support this ergogenic effect. The explanation for this divergence appears to be multifactorial, although it is always linked to methodological characteristics. Study design (crossover or parallel groups), individual variability of muscular creatine content, chronic high meat intake, sample size, exercise protocol characteristics (body weight dependence and time between series), and gender and age all differ between studies and are potentially the variables responsible, to differing extents, for the discrepancies observed in the literature. Studies involving young males, with parallel group design, adequate statistical power, control of the incorporation of creatine into muscles, food intake assessment and intermittent exercise protocols in which performance is independent of body weight and with rest-recovery intervals of 1 to 6 minutes, usually produce positive results. The many methodological factors which can contribute to divergence on the ergogenic effects of creatine should be considered in futures studies, as well as when prescribing creatine supplementation.

Resumo Após breve revisão da literatura existente acerca dos efeitos da suplementação de creatina no rendimento em atividades intermitentes de alta intensidade, o objetivo principal dessa revisão foi discutir diferenças metodológicas dos estudos que possam explicar a divergência encontrada na literatura. Os efeitos da suplementação de creatina no exercício intermitente de alta intensidade são bastante investigados. Embora existam inúmeros achados demonstrando a efi cácia desse suplemento nesse tipo de atividade, outras tantas evidências não suportam tal efeito ergogênico. A explicação para essa divergência parece ser multifatorial, porém sempre ligada às questões metodológicas. O modelo do estudo (crossover ou grupos independentes paralelos), a variabilidade individual no conteúdo muscular de creatina, o alto consumo de carnes, o tamanho da amostra, as características do protocolo de exercício (dependência do peso corporal e tempo de intervalo entre as séries), e diferenças de gênero e idade entre estudos são potenciais variáveis que explicam, em maior ou menor magnitude, a discrepância na literatura. Estudos envolvendo homens jovens, com modelo de grupos paralelos, poder estatístico satisfatório, controle da incorporação de creatina muscular, avaliação do consumo alimentar e protocolos de exercícios intermitentes máximos, cujo rendimento não depende do peso corporal, com intervalos de recuperação entre 1 a 6 minutos, tendem a apresentar resultados positivos. Os diversos fatores metodológicos que podem contribuir para a divergência acerca do tema devem ser considerados quando da realização de futuros estudos, bem como no momento da prescrição desse suplemento.

Reference Key
brum2008revista<b> Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Patrícia Chackur Brum;Emerson Franchini;Júlio César Batista Ferreira;Fabiana Braga Benatti;Bruno Gualano;Antonio Herbert Lancha Junior
Journal journal of proteome research
Year 2008
DOI
DOI not found
URL
http://www.periodicos.ufsc.br/index.php/rbcdh/article/view/4167/3502
Keywords
diet supplements sportsmedicine (general) excercício físico

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