multiple system atrophy: clinical-radiological correlation. report of two cases atrofia de múltiplos sistemas: correlação clínico-radiológica. estudo de dois casos

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ID: 226739
2007
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Abstract
Multiple system atrophy (MSA) is a sporadic, neurodegenerative disorder, clinically characterized by parkinsonian, autonomic, cerebellar and pyramidal signs. We describe two patients showing different presentations of the same disease. The patient on case 1 presents features of MSA-C or olivopontocerebellar atrophy with the pontine "cross sign" on brain MRI. The second case reports a patient presenting MSA-P or striatonigral degeneration and the brain MRI shows lenticular nucleus sign alteration. We think that brain MRI might increase the accuracy diagnostic of MSA.
A atrofia de múltiplos sistemas (AMS) é uma doença neurodegenerativa esporádica caracterizada clinicamente por diferentes combinações de sinais parkinsonianos, autonômicos, cerebelares e piramidais. Descrevemos dois pacientes apresentando diferentes formas clínicas da mesma afecção. O caso 1 tem características da AMS-C ou atrofia olivopontocerebelar, apresentando na ressonância magnética (RM) o "sinal da cruz" na ponte. Já o caso 2 tem AMS-P ou degeneração nigro-estriatal, a RM mostra alteração do sinal no núcleo lentiforme entre outras alterações. Acreditamos que a RM cerebral possa contribuir para o melhor diagnóstico da AMS.
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Authors Adolfo V. de Albuquerque, Marcos R.G. de Freitas, Daniel Cincinatus, Maria Beatriz B. Harouche
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Journal communications in computer and information science
Year 2007
DOI
10.1590/S0004-282X2007000300029
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300029
Keywords
multiple system atrophy neuropsychiatry biological psychiatry

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