ham/tsp: association between white matter lesions on magnetic resonance imaging, clinical and cerebrospinal fluid findings
Clicks: 193
ID: 225899
2012
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Emerging Content
30.0
/100
193 views
21 readers
AI Quality Assessment
Not analyzed
Readership in this journal
EmergingRanked #150 of 475 articles by views in communications in computer and information science
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 475 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
OBJECTIVE: To investigate the association between clinical data, white matter lesions and inflammatory cerebrospinal fluid (CSF) findings in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHOD: We studied brain and cervical spinal cord on magnetic resonance imaging (MRI) and CSF examinations of 28 Brazilian HAM/TSP patients. RESULTS: The majority of patients had severe neurological incapacity with EDSS median of 6.5 (3-8). The brain MRI showed white matter lesions (75%) and atrophy (14%). The preferential brain location was periventricular. Cervical demyelination lesions occurred in 11% of the cases, and cervical atrophy in 3.5%. One patient had enhancement lesions on T1 cervical spinal cord MRI. Cases with spinal cord lesions had signs of acute CSF inflammation. The brain white matter lesions predominated in the patients with higher age. CONCLUSION: Our data suggest that an active inflammatory process is associated with the cervical spinal cord lesions in HAM/TSP. The brain abnormalities are not related to the clinical picture of HAM/TSP.
| Reference Key |
puccioni-sohler2012arquivosham/tsp:
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Marzia Puccioni-Sohler;Emerson Gasparetto;Mauro Jorge Cabral-Castro;Carla Slatter;Cecilia M. Vidal;Romeu Domingues Cortes;Bruce R. Rosen;Caterina Mainero |
| Journal | communications in computer and information science |
| Year | 2012 |
| DOI |
10.1590/S0004-282X2012000400004
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.