superbugs causing ventilator associated pneumonia in a tertiary care hospital and the return of pre-antibiotic era!

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ID: 225628
2015
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Ranked #115 of 129 articles by views in bjog : an international journal of obstetrics and gynaecology

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Abstract
The rise in super bugs causing Ventilator-Associated Pneumonia (VAP) is a major cause of mortality and morbidity despite recent advances in management owing to the looming ′antibiotic apocalypse′. The aetiology and susceptibility pattern of the VAP isolates varies with patient population, type of intensive care unit (ICU) and is an urgent diagnostic challenge. The present study carried out for a period of one year in a tertiary care hospital, enrolled patients on mechanical ventilation (MV) for ≥48 hrs. Endotracheal aspirates (ETA) from suspected VAP patients were processed by semi quantitative method. Staphylococus aureus, members of Enterobacteriaceae were more common in early onset VAP (EOVAP), while Nonfermenting Gram negative bacilli (NFGNB) were significantly associated with late onset VAP (LOVAP). Most of the isolates were multi drug resistant (MDR) super bugs. With limited treatment options left for this crisis situation like the pre-antibiotic era; it is an alarm for rational antibiotic therapy usage and intensive education programs.
Reference Key
qureshi2015indiansuperbugs Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;S Qureshi;C Agrawal;M Madan;A Pandey;H Chauhan
Journal bjog : an international journal of obstetrics and gynaecology
Year 2015
DOI
10.4103/0255-0857.153566
URL
http://www.ijmm.org/article.asp?issn=0255-0857;year=2015;volume=33;issue=2;spage=286;epage=289;aulast=Qureshi
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