estudo histopatológico do trajeto de biópsia de tumores musculoesqueléticos malignos histopathological study on biopsy track in malignant musculoskeletal tumors

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ID: 225389
2009
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Abstract
OBJETIVO: Verificar se havia risco de contaminação por células neoplásicas no trajeto da biópsia e estudar as alterações histológicas locais. MÉTODOS: Realizou-se um estudo prospectivo com trajetos de biópsias de pacientes operados por tumores musculoesqueléticos malignos no Instituto de Ortopedia e Traumatologia da Faculdade de Medicina da Universidade de São Paulo no período de abril de 2006 a abril de 2007. Foram estudados por histopatologia 25 casos. RESULTADOS: Houve implante de células neoplásicas em 32% dos trajetos. As alterações histológicas mais comuns nos casos positivos foram classificadas como: fibrose acentuada, componente inflamatório leve e neovascularização acentuada. CONCLUSÃO: Sugerimos a ressecção tradicional oncológica do trajeto junto com a peça.
OBJECTIVE: To investigate whether there is any risk of seeding by neoplasic cells along biopsy tracks and to study local histological abnormalities. METHODS: This was a prospective study on biopsy tracks in patients who underwent operations due to malignant musculoskeletal tumors between April 2006 and April 2007. RESULTS: Neoplasic cell implantation occurred in 32% of the tracks. The most common histological abnormalities in positive cases were classified as severe fibrosis, mild inflammatory component and severe neovascularization. CONCLUSION: We suggest that traditional oncological resection of the track should be carried out together with excision of the specimen.
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Authors ;Marcelo Barbosa Ribeiro;Cláudia Regina G.C.M. de Oliveira;Renée Zon Filippi;André Mathias Baptista;Marcelo Tadeu Caiero;Carlos Fernando Saito;Sérgio Antonio Barbosa do Nascimento;Olavo Pires de Camargo
Journal current opinion in food science
Year 2009
DOI
10.1590/S1413-78522009000500005
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