molecular differences in the kras gene mutation between a primary tumor and related metastatic sites – case report and a literature review
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ID: 224995
2010
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Abstract
In recent years the the set of diagnostic tools in colorectal cancers has been extended by the assessment ofthe KRAS gene status. Currently it is a necessary step in order to qualify patients for the targeted therapy. The results ofthe analysis of several studies revealed a high rate of compliance of the KRAS gene mutational status in primary and metastatictumors. In this paper we present a rare case of incompatibility of the KRAS mutations in the primary tumor located inthe colon and metastatic changes in the liver.
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kosakowska2010foliamolecular
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| Authors | ;Ewa Anna Kosakowska;Rafal Stec;Radoslaw Charkiewicz;Marta Skoczek;Lech Chyczewski |
| Journal | reviews on recent clinical trials |
| Year | 2010 |
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