isolation, identification and anti-candidal activity of filamentous fungi from saudi arabia soil

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ID: 224753
2018
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Abstract
Ten fungal strains; namely, Penicillium melinii, Petriella setifera, Aspergillus pseudo-niger, Alternaria chlamydospora, Pythium nayoroense, Phoma glomerata, Mucor ramosissimus, Mucor racemosus, Fusarium chlamydosporum and Rhizopus azygosporus were isolated from soil. The extra- and intra-cellular extracts of the fungal strains grown on malt extract and yeast-extract sucrose media were screened for their anticandidal activity against different clinically-isolated Candida species. Most of the fungal extracts showed activity against different Candida species. However, the fungal strains grew on malt extract showed greater activities than those grew on yeast extract sucrose media. The activity of the intracellular was higher than the extracellular metabolites. All fungal extracts (extra and intra) were similar in chemical constituent; they contained carbohydrates and/or glycosides, unsaturated sterols and/or triterpens, tannins and traces of coumarins. Alkaloids, flavonoids, saponins, anthraquinones and cardenolides were no detected. The intra-cellular extracts contained more compounds than the extra-cellular extracts.
Reference Key
al-enazi2018saudiisolation, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Nouf M. Al-Enazi;Amani S. Awaad;Monerah R. Al-Othman;Nour K. Al-Anazi;Saleh I. Alqasoumi
Journal International journal for quality in health care : journal of the International Society for Quality in Health Care
Year 2018
DOI
10.1016/j.jsps.2017.12.003
URL
http://www.sciencedirect.com/science/article/pii/S1319016417302116
Keywords
anticandidal activity pharmacology

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