photodynamic therapy for non-melanoma skin cancers

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ID: 222731
2016
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Abstract
Non‐melanoma skin cancer (NMSC) is traditionally treated with surgical excision. Nonsurgical methods such as cryotherapy and topical chemotherapeutics, amongst other treatments, are other options. Actinic keratosis (AKs) are considered precancerous lesions that eventually may progress to squamous cell carcinoma (SCC). Photodynamic therapy (PDT) offers an effective treatment for AKs, and is also effective for superficial basal cell carcinoma (BCC). Nodular BCC and Bowen’s disease (SCC in situ) have shown acceptable response rates with PDT, although recurrence rates are higher for these two NMSC subtypes. Methylaminolevulinate (MAL) PDT is a more effective treatment option than 5‐aminolevulinic acid (ALA) PDT for nodular BCC. Several studies have shown that PDT results in superior cosmetic outcomes compared to surgical treatment. PDT is overall well‐tolerated, with pain being the most common side effect.
Reference Key
cohen2016cancersphotodynamic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Diana K. Cohen;Peter K. Lee
Journal The Journal of investigative dermatology
Year 2016
DOI
10.3390/cancers8100090
URL
http://www.mdpi.com/2072-6694/8/10/90
Keywords
photodynamic therapy basal cell carcinoma Oncology including cancer and carcinogens tumors

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