medicamentos quirais: da dimensão química à discussão política chiral drugs: from the chemical dimension to political discussion

Clicks: 271
ID: 221941
1996
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Abstract
São discutidos aspectos conceituais dos medicamentos quirais, correspondendo a substâncias enantiomericamente puras, constantes de apenas um dos isômeros, dextrógiro (R) ou levógiro (S). O impacto no mercado mundial, que hoje atinge um contingente de US$ 35,6 bilhões, correspondente a aproximadamente 20% do total, às custas de medicamentos quirais, é ressaltado pelos autores como significativo das tendências atuais. A expansão crescente do mesmo leva a crer que existe uma tendência nítida a que a produção de medicamentos quirais possa, em breve, representar uma nova forma de domínio por parte das empresas hegemônicas, impactando definitivamente o mercado dos produtos sob proteção patentária e inviabilizando a política de crescimento mundial de medicamentos genéricos. Finalizando, é levantada a relação entre os medicamentos quirais e as misturas racêmicas, chamando a atenção para a necessidade de incorporar esta dimensão química no âmbito da discussão das políticas públicas, considerando também a capacidade instalada em centros de pesquisa e universidades brasileiras.
Conceptual aspects regarding chiral drugs are discussed referring to enantiomerically pure substances, containing only one isomer, with optical orientation to the right (R) or left (S). Impact on world market, that means today over US$ 35 billions, or near 20% of total market with chiral drugs, is discussed as significative of actual trends. Growing expansion of this matter makes us think that there exists a clear trend that will lead chiral drugs to represent a new form of market domination, mainly regarding patent protection and bypassing crescent generic drug market policies. Finally, the question regarding chiral drugs and racemic mixtures is arised, calling attention for the need to incorporate this chemical dimension within health policy discussion, also considering brazilian capacity in research centers and universities.
Reference Key
bermudez1996cadernosmedicamentos Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Jorge A. Z. Bermudez;Paulo Barragat
Journal iberian conference on information systems and technologies, cisti
Year 1996
DOI
10.1590/S0102-311X1996000100015
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X1996000100015
Keywords
pharmaceutical industry industria farmacéutica chiral drugs

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