efficacy of goniosynechialysis in the treatment of chronic angle-closure glaucoma: a five-case report eficácia da goniossinequiálise no tratamento do glaucoma crônico de ângulo fechado: relato de cinco casos

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ID: 219026
2013
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Abstract
We retrospectively analyzed the clinical data of five patients with chronic angle-closure glaucoma who underwent goniosynechialysis (GSL). The patients presented a circumferential synechial angle-closure for less than or up to six months due to an acute primary angle-closure and a minimum six month follow up after GSL. After an average follow-up was of 32.4±13.9 months, visual acuity improved in four (80%) eyes. Before GSL, the intraocular pressure (IOP) varied from 34 to 58 mmHg. After GSL, the IOP varied from 8 to 44 mmHg. IOP was normalized by GSL with or without medication in 80% of the eyes. Before GSL, all patients were on maximum antiglaucomatous treatment including the use of 250 mg of oral acetazolamide three times daily. After GSL, three patients no longer required antiglaucomatous medication and one needed to use one topical antiglaucomatous medication. GSL was effective and safe in four patients and unsuccessful in one patient. An increase of the GSL success rate occurs when it is associated with phacoemulsification and intraocular lens implantation.
Analisamos retrospectivamente os dados clínicos de cinco pacientes com seio camerular fechado por sinéquias anteriores periféricas (SAP) secundárias à crise aguda de fechamento angular primário e submetidos à goniossinequiálise (GSL). Os pacientes apresentavam fechamento sinequial circunferencial por seis meses ou menos e foram acompanhados, no mínimo, por seis meses após a GSL. Após um acompanhamento médio de 32.4±13.9 meses, a acuidade visual melhorou em quatro (80%) olhos. Antes da GSL, a pressão intraocular (Po) variou de 34 a 58 mmHg. Após a GSL, a Po variou de 8 a 44 mmHg. A Po foi normalizada pela GSL com ou sem medicação em 80% dos olhos. Antes da GSL, todos os pacientes estavam sob tratamento antiglaucomatoso máximo incluindo o uso de 250 mg de acetazolamida por via oral três vezes ao dia. Após a GSL, três pacientes não mais necessitaram de medicação antiglaucomatosa e um paciente necessitou usar apenas uma medicação tópica antiglaucomatosa. A GSL foi eficaz e segura em quatro pacientes e não foi eficaz em um paciente. Ocorre um aumento da taxa de sucesso da GSL quando ela é associada à facoemulsificação com implante de lente intraocular.
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cronemberger2013revistaefficacy Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Sebastião Cronemberger;Artur Furst Loredo;Daniela Silveira de Faria;Nassim Calixto
Journal the european journal of neuroscience
Year 2013
DOI
DOI not found
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-72802013000100012
Keywords
glaucoma intraocular pressure

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