effects of clinoptilolite treatment on oxidative stress after partial hepatectomy in rats
Clicks: 183
ID: 218639
2011
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
183 views
11 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #165 of 248 articles by views in journal of molecular structure
Most read
Least read
Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 248 in total.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
Background/Objective: Clinoptilolite is a natural zeolite crystal. Cytoprotective effects of clinoptilolite have been reported. However, so far there are no data about the effects of clinoptilolite treatment on oxidative stress after partial hepatectomy. In this experimental study, the effects of clinoptilolite treatment after partial hepatectomy on oxidative stress were evaluated.
Methods: There were four experimental groups (n=8): Group S, the sham group; Group H, the hepatectomy group; Group HC, the clinoptilolite treatment after partial hepatectomy group; and Group CS, the clinoptilolite-treated sham group. A 70% partial hepatectomy was performed for Group H and HC. Clinoptilolite (5 mg/kg) was given to the rats orally (via gavage tube) twice a day for 10 days after hepatectomy. Malondialdehyde (MDA), Cu-Zn super oxide dismutase (SOD), and glutathione (GSH) levels were assessed to evaluate oxidative stress.
Results: Plasma and liver tissue MDA levels of Group HC were significantly lower than the H group (p=0.018 and p=0.000, respectively). Liver tissue Cu-Zn SOD activity and GSH levels of Group HC were significantly higher than Group H (p=0.003, p=0.007, respectively).
Conclusion: Clinoptilolite administration reduces oxidant activity and supports antioxidant response after partial hepatectomy.
| Reference Key |
saribeyoglu2011asianeffects
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Kaya Saribeyoglu;Erman Aytac;Salih Pekmezci;Seha Saygili;Hafize Uzun;Gulsen Ozbay;Seval Aydin;Hakki Oktay Seymen |
| Journal | journal of molecular structure |
| Year | 2011 |
| DOI |
10.1016/j.asjsur.2011.11.007
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.