excrecion fraccional de urea baja en hiponatremia inducida por hipotiroidismo

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ID: 218241
2005
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Abstract
ABSTRACTHypothyroidism can cause disturbance of renal hemodinamics, kidney histology, water and electrolyte metabolism, being hyponatremia and glomerular filtration reduction their low prevalent but most significant consequences. All these changes are largely corrected by substitution of exogenous thyroid hormone.Fractional excretion of urea (FEU) is a useful index in the evaluation of hyponatremia. However, it was not still reported in the literature the FEU value in hyponatremia induced by hypothyroidism. Because of that we presented a case report showing that the value of FEU and fractional excretion of sodium (FENa) were low (FEU: 29%) and high (FENa: 2.2 %) respectively in a severe hypothyroid patient. Treatment based on thyroid hormone normalized both indeces.RESUMEN:El hipotiroidismo puede causar alteraciones del metabolismo del agua, los electrolitos, la hemodinamia e histología renales, siendo la hiponatremia y la reducción del filtrado glomerular sus consecuencias más significativas, pero poco prevalentes. Todos estos cambios son corregibles con el suministro de hormona tiroidea exógena.La excreción fraccional de urea (EFU) es un índice útil en la evaluación de la hiponatremia, pero no se ha descripto aun el valor que este índice alcanza en la hiponatremia inducida por hipotiroidismo. En el presente reporte mostramos que la EFU y excreción fraccional de sodio (EFNa) fueron baja (EFU: 29%) y alta (EFNa: 2.2%) respectivamente en un paciente que padecía hipotiroidismo severo. El tratamiento con hormona tiroidea normalizó el valor de ambos índices.
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Authors ;Musso CG;Macías Núñez JF;Imperiali N;Algranati L
Journal animal models and experimental medicine
Year 2005
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