ways of treating iga nephropathies

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ID: 211416
2000
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Abstract
Summary: Treatment options for IgA nephropathy (IgAN) must take into consideration the pathophysiology, namely the role of eicosanoids, angiotensin II and monocyte-macrophages releasing reactive oxygen species (ROS). Angiotensin converting enzyme inhibitors and early corticosteroid usage are prime therapies. Tonsillectomy should be considered. Other components of a therapeutic cocktail could be; (a) thromboxane antogonist, (b) leukotriene antagonist, (c) platelet activating factor antagonist, (d) an anti-oxidant and (e) an anti-fibrotic agent like pentoxyfylline. In the new millenium, there will be focus on anti-proliferative measures like platelets dependent growth factor aptamers. For unusual cases with rapid progression, the use of FK-506 or mycophenolate mofetil can be considered.
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Authors ;Wardle E
Journal 15th ibero-american conference on software engineering, cibse 2012
Year 2000
DOI
DOI not found
URL
http://www.sjkdt.org/article.asp?issn=1319-2442;year=2000;volume=11;issue=3;spage=325;epage=333;aulast=Wardle
Keywords
Medicine reactive oxygen species angiotensin ii complement eicosanoids

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