mudanças na concentração plasmática de zinco e ácido fólico em adolescentes grávidas submetidas a diferentes esquemas de suplementação changes in plasma zinc and folic acid concentrations in pregnant adolescents submitted to different supplementation regimens

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ID: 211163
2003
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Abstract
O estado nutricional do zinco e ácido fólico foi avaliado em 74 adolescentes grávidas, de baixa renda, entre 13 e 18 anos, atendidas no pré-natal na Maternidade Dona Evangelina Rosa, Teresina, Piauí, Brasil. Para avaliar os diferentes esquemas de suplementação no estado nutricional das adolescentes, estas foram aleatoriamente distribuídas em cinco grupos: Os grupos I e II receberam quantidades iguais de ácido fólico (250µg) e diferentes concentrações em ferro (sulfato ferroso) 120 e 80mg, respectivamente. Os grupos III e IV receberam quantidades iguais de ácido fólico (250µg) associado ao sulfato de zinco (5mg) e ferro nas concentrações de 120 e 80mg, respectivamente e o grupo V, apenas ferro, 120mg (rotina). Os resultados quanto ao zinco mostraram uma redução na sua concentração plasmática, sendo esse declínio significativo apenas nos grupos que não receberam o mineral. Quanto ao uso associado de ferro/ácido fólico e ferro/ácido fólico/zinco, verifica-se excelente resposta no estado nutricional referente ao ácido fólico, sendo esse efeito mais expressivo nos grupos que receberam ácido fólico associado ao zinco, sugerindo a possível participação do zinco no aproveitamento da vitamina.
Zinc and folic acid nutritional status was evaluated in 74 low-income pregnant adolescents ranging from 13 to 18 years of age who received prenatal care at the Evangelina Rosa Maternity Hospital in Teresina, Piauí State, Brazil. In order to evaluate the effects of different supplementation regimens on nutritional status, the adolescents were distributed into five groups. Groups I and II received equal amounts of folic acid (250µg) and different doses of iron (ferrous sulfate), 120 and 80mg, respectively. Groups III and IV received equal amounts of folic acid (250µg) associated with zinc sulfate and iron at doses of 120 and 80mg, respectively, while group V received only 120mg of iron (routine dosage). There was a reduction in the zinc plasma concentration, and this decline was significant only in those groups which did not receive zinc supplementation. In relation to combination iron/folic acid and iron/folic acid/zinc, an excellent response was observed for folic acid, and this effect was larger in the groups that received folic acid combined with zinc, suggesting a possible role for zinc in folic acid metabolism.
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nogueira2003cadernosmudanas Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Nadir do Nascimento Nogueira;Joaquim Vaz Parente;Sílvia Maria Franciscato Cozzolino
Journal iberian conference on information systems and technologies, cisti
Year 2003
DOI
10.1590/S0102-311X2003000100017
URL
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2003000100017
Keywords
Zinc folic acid iron estado nutricional pregnancy in adolescence

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