incidence of fluoroquinolone resistance in pseudomonas aeruginosa from urinary tract infections
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2016
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Abstract
The susceptibility of 105 Pseudomonas aeruginosa isolates collected from patients with urinary tract infections
was assessed by determination of minimum inhibitory concentration (MICs) using agar dilution method against the
following agents: norfloxacin, ofloxacin, ciprofloxacin and pefloxacin.
Resistance rates of P. aeruginosa to tested fluoroquinolones was fairly uniformly distributed between compounds as
followed: norfloxacin - 52.4%, ofloxacin- 49.5%, ciprofloxacin - 51.4%, pefloxacin - 49.5%. Analysis of cross-resistance
in P. aeruginosa showed a correlated magnitude of resistance between fluoroquinolones. Among the P.aeruginosa strains
the number of those showing simultaneously resistance to all tested agents is high (n=50).
The significant increase in fluoroquinolone resistance probably reflects the widspread use of this agent and the clinical
use of these compunds should be carefully monitored since most bacterial strains shows cross-resitance.
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poiata2016analeleincidence
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|---|---|
| Authors | ;Antonia Poiata;Ioana Badicut |
| Journal | international journal of online engineering (ijoe) |
| Year | 2016 |
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