examination of the lipid profile in pregnant obese women, considering the allele status of the genes of angiotensin-converting enzyme (ace i / d) and plasminogen-1 (pa-1 4g / 5g) activator-inhibitor
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2018
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Abstract
Changes in the lipid profile in pregnant women, with and without obesity, have been studied depending on the angiotensin-converting enzyme (ACE) gene I/ D polymorphism and the 4G5G polymorphism of the plasminogen activator inhibitor type I (PAI-1). The combination of the D-allele of the ACE gene and the 5G allele of the PAI-1 gene is a risk factor of increasing total cholesterol in pregnant women, regardless of the obesity class, and of increasing triglycerides in pregnant women without obesity. The presence of the D-allele of the ACE gene in the haplotype, regardless of the combinations of the genotypes of the PAI-1 gene, is a risk factor of increasing triglycerides in pregnant women with obesity.
| Reference Key |
bulyk2018archivesexamination
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| Authors | ;Tetiana S. BULYK;Vasyl Y. RYNZHUK;Marina D. GRESKO;Larisa V. RYNZHUK;Larisa P. SYDORCHUK;Vitaliy V. MAKSIMYUK;Yuriy O. MALYSHEVSKYI;Mariana I. KRYVCHANSKA;Violeta G. KHOMENKO;Kateryna V. VLASOVA;Tetiana A. GLUSHCHENKO;Victor M. BATIG |
| Journal | advances in electrical and electronic engineering |
| Year | 2018 |
| DOI |
10.31688/ABMU.2018.53.2.05
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