the tip of the iceberg: clinical implications of genomic sequencing projects in head and neck cancer

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ID: 203398
2015
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Abstract
Recent genomic sequencing studies have provided valuable insight into genetic aberrations in head and neck squamous cell carcinoma. Despite these great advances, certain hurdles exist in translating genomic findings to clinical care. Further correlation of genetic findings to clinical outcomes, additional analyses of subgroups of head and neck cancers and follow-up investigation into genetic heterogeneity are needed. While the development of targeted therapy trials is of key importance, numerous challenges exist in establishing and optimizing such programs. This review discusses potential upcoming steps for further genetic evaluation of head and neck cancers and implementation of genetic findings into precision medicine trials.
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birkeland2015cancersthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Andrew C. Birkeland;Megan L. Ludwig;Taha S. Meraj;J. Chad Brenner;Mark E. Prince
Journal The Journal of investigative dermatology
Year 2015
DOI
10.3390/cancers7040879
URL
http://www.mdpi.com/2072-6694/7/4/0879
Keywords
Cancer targeted therapy precision medicine hnscc tcga Oncology including cancer and carcinogens tumors

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