the effects of artemisia aucheri extract on hepatotoxicity induced by thioacetamide in male rats

Clicks: 176
ID: 200857
2013
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #34 of 35 articles by views in Anatolian journal of cardiology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Objective: Liver is an important organ that is exposed to many oxidant and carcinogenic agents, thus antioxidant compounds are beneficial for liver health. Artemisia contains flavonoid compounds and anti-diabetic, antioxidant, and anti-inflammatory properties. Due to possessing terpene and sesquiterpene compounds, this plant has antioxidant properties. This study was done to investigate the effects of Artemisia plant extract on thioacetamide-induced hepatotoxicity in Wistar rats. Materials and Methods: For induction of hepatotoxicity, 50 mg/kg thioacetamide was injected intraperitoneally (i.p).After extraction and purification, the hydroalcoholicextract was injected i.p. at 100, 200, and 300 mg/kg doses for 21 days together with thioacetamide at 50 mg/kg dose in the last 3 days. After blood sampling and separation of serum, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin, and total protein concentrations were measured. Results: Significant decreases in aminotransferase and alkaline phosphatase activities and significant increases in the concentration of albumin and total protein in groups treated with the extract compared with thioacetamide-treated group were observed (p
Reference Key
rezaei2013avicennathe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Azam Rezaei, Shahnaz ShekarForoush, Saeed Changizi Ashtiyani, Hydar Aqababa, Ali Zarei, Maryam Azizi, Hasan Yarmahmodi
Are you one of these authors? Claim your profile
Journal Anatolian journal of cardiology
Year 2013
DOI
DOI not found
URL
http://ajp.mums.ac.ir/pdf_766_7ab1dd93b910478ff0ee8843a7faa0a4.html
Keywords
phenolic compounds rat pharmacology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.