factors affecting survival of women diagnosed with breast cancer in el-minia governorate, egypt

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ID: 200310
2011
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Abstract
Objectives: This study was conducted to determine breast cancer survival time and the association between breast cancer survival and socio-demographic and pathologic factors among women, in El-Minia, Egypt. While there has been much researches regarding prognostic factors for breast cancer but the majority of these studies were from developed countries. El-Minia has a population of approximately 4 million. To date, no research has been performed to determine breast cancer survival and the factors affecting it in El-minia. Methods : This retrospective study used data obtained from the cancer registry in the National Institute of Oncology in El-Minia and included 1207 women diagnosed with first primary breast cancer between 1 st January 2005 and 31st December 2009 and followed to 30 th June 2010. The association between survival and sociodemographic and pathological factors and distant metastasis at diagnosis, and treatment options was investigated using unifactorial chi-square test and multi-factorial (Cox regression) analyses. Kaplan-Meier analysis was used to compare survival time among different groups. Results: Median survival time was 83.8 ± 3.2. Cox regression showed that high vs low educational level (Hazard ratio (HR)= 0.35, 95% CI; 0.27-0.46), metastases to bone (HR = 3.22, 95% CI: 1.71-6.05), metastases to lung (HR= 2.314, 95% CI: 1.225-4.373), tumor size (≤ 2 cm vs ≥ 5 cm: HR = 1.4, 95% CI: 1.1-1.8) and number of involved nodes (1 vs > 10 HR = 5.21, 95%CI: 3.1-9.01) were significantly related to survival. Conclusions: The results showed the need to develop screening programs and standardized treatment regimens in a tax-funded health care system.
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seedhom2011internationalfactors Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Amany Edward Seedhom;Nashwa Nabil Kamal
Journal italian journal of animal science
Year 2011
DOI
DOI not found
URL
http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2011;volume=2;issue=3;spage=131;epage=138;aulast=Seedhom
Keywords
Breast cancer survival

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