pathogenicity, host responses and implications for management of enterohemorrhagic escherichia coli o157:h7 infection
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ID: 199064
2013
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Abstract
Enterohemorrhagic Escherichia coli serotype O157:H7 is a food- and waterborne pathogen that causes significant morbidity and mortality in both developing and industrialized nations. The present review focuses on the history, epidemiology and evolution of the pathogen; provides a mechanistic overview of major virulence factors (including Shiga toxins, locus of enterocyte effacement pathogenicity island and pO157 plasmid); discusses host immune responses to infection; considers available animal models; and provides an overview of current and potential future management considerations.
| Reference Key |
ho2013canadianpathogenicity,
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|---|---|
| Authors | ;Nathan K Ho;Aleah C Henry;Kathene Johnson-Henry;Philip M Sherman |
| Journal | indian journal of pharmacology |
| Year | 2013 |
| DOI |
10.1155/2013/138673
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| URL | |
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